Pomalidomide 4'-alkyl-C6-acid

SL-11299

Pomalidomide 4'-alkyl-C6-acid, >98%

CAS No. : [2225940-50-9]

Synonyms : Pomalidomide-C6-COOH

IUPAC Name : 7-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)heptanoic acid

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Applications : Pomalidomide-C6-COOH acts as a cereblon (CRBN) ligand derived from Pomalidomide, enabling recruitment of the CRBN protein. By attaching pomalidomide-6-OH to a protein ligand via a linker, it is possible to create PROTAC molecules.

References : Xiaojuan Q. et al.: Eur. J. Med. Chem., 218, 113328, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.