Pomalidomide 4'-alkyl-C8-acid

SL-11301

Pomalidomide 4'-alkyl-C8-acid, >98%

CAS No. : [2305936-70-1]

Synonyms : Pomalidomide-C8-COOH

IUPAC Name : 9-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)nonanoic acid

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25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : Pomalidomide 4'-alkylC8-acid is an E3 ubiquitin ligase ligand-linker conjugate incorporating Pomalidomide. As a third-generation immunomodulatory agent, Pomalidomide functions as a molecular glue. It interacts with the E3 ligase cereblon, facilitating the targeted degradation of the critical Ikaros transcription factor.

References : Zhu Y. X. et al.: Leuk Lymphoma, 54(4), 683-7, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.