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Pomalidomide-C11-NH2 hydrochloride

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SL-11319

Pomalidomide-C11-NH2 hydrochloride, >98%

CAS No. : [2722611-55-2]

Synonyms : Pomalidomide 4'-alkyl-C11-amine hydrochloride

IUPAC Name : 4-((11-Aminoundecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride

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Chemical Properites
Mol. Formula :
C24H34N4O4 • HCl
Mol. Weight :
479.02
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Pomalidomide-C11-NH2 hydrochloride is a cereblon (CRBN) ligand derived from Pomalidomide, used to recruit CRBN protein. It can be linked by a connector to other ligands to create PROTACs.

References : Chotitumnavee J. et al.: Chem Commun (Camb), 58(29), 4635-4638, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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