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Pomalidomide-C2-NH2 hydrochloride

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Pomalidomide-C2-NH2 hydrochloride, >98%

CAS No. : [2305369-00-8]

Synonyms : Cereblon ligand-linker conjugates 15 hydrochloride

IUPAC Name : 4-((2-Aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride

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Chemical Properites
Mol. Formula :
C15H16N4O4 • HCl
Mol. Weight :
352.78
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Pomalidomide-C2-NH2 hydrochloride is an artificially created E3 ligase ligand-linker conjugate that combines a cereblon ligand derived from Pomalidomide with a linker for use in PROTAC technology.

References : Shibata N. et al.: J. Med. Chem., 61(2), 543-575, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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