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Pomalidomide-C3-alkyne

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SL-11322

Pomalidomide-C3-alkyne, >98%

CAS No. : [2154356-75-7]

IUPAC Name : 2-(2,6-Dioxopiperidin-3-yl)-4-(pent-4-yn-1-ylamino)isoindoline-1,3-dione

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C18H17N3O4
Mol. Weight :
339.35
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Pomalidomide-C12-NH2 hydrochloride is the E3 ligase ligand-linker conjugate of PROTAC KRAS G12C degrader-1 (HY-139186). PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C degrader.

References : Zeng M. et al.: Cell Chem Biol., 27(1), 19-31.e6, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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