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Pomalidomide-C6-O-C5-O-C4-COOH

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SL-11303

Pomalidomide-C6-O-C5-O-C4-COOH, >98%

CAS No. : [2375774-54-0]

IUPAC Name : 5-((5-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)oxy)pentyl)oxy)pentanoic acid

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Chemical Properites
Mol. Formula :
C29H41N3O8
Mol. Weight :
559.66
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Pomalidomide-C6-O-C5-O-C4-COOH is an E3 ligase ligand-linker conjugate that contains a pomalidomide-based cereblon ligand and a linker. This compound can be used to synthesize PROTACs.

References : Steinebach C. et al.: Chem Commun (Camb), 55(12), 1821-1824, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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