Pomalidomide hydrolysis impurity 1

SL-11252

Pomalidomide hydrolysis impurity 1, >98%

CAS No. : [918314-45-1]

IUPAC Name : 5-Amino-4-(4-amino-1,3-dioxoisoindolin-2-yl)-5-oxopentanoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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Applications : This is an impurity of Pomalidomide, which is a third-generation immunomodulatory agent that acts as molecular glue by binding to E3 ligase cereblon and promoting degradation of Ikaros transcription factors.

References : Zhu Y. X. et al.: Leuk Lymphoma, 54(4), 683-7, 2013; Hernandez-Ilizaliturri F. et al.: Clin Cancer Res., 11(16), 5984-92., 2005; Schafer P. H. et al.: J. Pharmacol Exp Ther. 305(3), 1222-32, 2003; Li Z. et al.: PLoS One, 8(8), e71754, 2013; Lu J. et al.: Chem Biol., 22(6), 755-63, 2015; Liu D. et al.: Gen Comp Endocrinol., 228, 1-8, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.