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Pomalidomide-PEG3-C2-NH2 TFA

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SL-11290

Pomalidomide-PEG3-C2-NH2 TFA, >98%

CAS No. : [2414913-97-4]

Synonyms : Cereblon ligand-linker conjugates 5 TFA; E3 ligase ligand-linker conjugates 30 TFA

IUPAC Name : 4-((2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate

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Chemical Properites
Mol. Formula :
C21H28N4O7 • CF3CO2H
Mol. Weight :
562.5
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Pomalidomide-PEG3-C2-NH2 TFA is a synthetic E3 ligase ligand-linker conjugate comprising a Pomalidomide based cereblon ligand and a 3-unit PEG linker. Pomalidomide-PEG3-C2-NH2 TFA can be used for the synthesis of PROTACs.

References : Li Y. et al.: J. Med. Chem., 62(2), 448-466, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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