Ponatinib

SI-4564

Ponatinib, >98% (HPLC)

CAS No. : [943319-70-8]

MDL No. : MFCD17215203

Synonyms : AP24534

IUPAC Name : 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	215.00		Back Order	Estimated to ship on 04 October 2026
5G	795.00		Back Order	Estimated to ship on 04 October 2026

Applications : Ponatinib is a potent, orally available multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.

References : O'Hare T. et al.: Cancer Cell 16(5), 401-412,2009; Gozgit J. M. et al.: Mol Cancer Ther., 10(6), 1028-1035,2011; Uchida T. et al.: Exp Hematol., 42(5), 369-379, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.