Ponatinib hydrochloride

SI-4566

Ponatinib hydrochloride, >98% (HPLC)

CAS No. : [1114544-31-8]

MDL No. : MFCD28656903

Synonyms : AP24534 hydrochloride

IUPAC Name : 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	95.00		Back Order	Estimated to ship on 04 October 2026
5G	325.00		Back Order	Estimated to ship on 04 October 2026

Applications : Ponatinib hydrochloride is a potent, orally available multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.

References : O'Hare T. et al.: Cancer Cell 16(5), 401-412,2009; Gozgit J. M. et al.: Mol Cancer Ther., 10(6), 1028-1035,2011; Uchida T. et al.: Exp Hematol. 42(5), 369-379, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.