Poselitinib

SI-6907

Poselitinib, >98% (HPLC)

CAS No. : [1353552-97-2]

Synonyms : LY-3337641; HM-71224

IUPAC Name : N-(3-((2-((4-(4-Methylpiperazin-1-yl)phenyl)amino)furo[3,2-d]pyrimidin-4-yl)oxy)phenyl)acrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Poseltinib irreversibly inhibits BTK with high potency (IC₅₀ = 1.95 nM) and effectively blocks BCR‑, FcR‑, and TLR‑dependent signaling pathways. Its oral activity and anti‑inflammatory profile make it a valuable tool for investigating BTK‑driven mechanisms in rheumatoid arthritis.

References : Kim Y. Y. et al.: Arthritis Res. Ther., 19(1), 211, 2017; Park J. K. et al.: Arthritis Res. Ther., 18, 91, 2016; Byun J. Y. et al.: Sci. Rep., 11(1), 18671, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.