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Pralatrexate

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SI-2765

Pralatrexate, >98% (HPLC)

CAS No. : [146464-95-1]

MDL No. : MFCD00920897

IUPAC Name : (2S)-2-(4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzamido)pentanedioic acid

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Chemical Properites
Mol. Formula :
C23H23N7O5
Mol. Weight :
477.47
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines.

References : Liu K. K-C. et al.: Bioorg. Med. Chem., 19(3), 1136-1154, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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