Praliciguat

SI-7934

Praliciguat, >98% (HPLC)

CAS No. : [1628730-49-3]

Synonyms : IW-1973

IUPAC Name : 1,1,1,3,3,3-Hexafluoro-2-(((5-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidin-4-yl)amino)methyl)propan-2-ol

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Praliciguat activates sGC to elevate cGMP levels through the NO–sGC pathway, leading to anti‑inflammatory, anti‑apoptotic, and vasodilatory effects. Its pharmacological profile supports its use in metabolic and cardiovascular disease models, including hypertension, diabetes, and heart failure.

References : Liu .G. et al.: Am. J. Physiol Renal Physiol., 319(4), F697-F711, 2020; Shea C. M. et al.: Am. J. Physiol Renal Physiol., 318(1), F148-F159, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.