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Prednisolone 17-carboxylic acid impurity

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Prednisolone 17-carboxylic acid impurity, >98%

CAS No. : [75448-51-0]

Synonyms : Prednisolone impurity @ RRT 2.0

IUPAC Name : (8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid

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Chemical Properites
Mol. Formula :
C20H26O4
Mol. Weight :
330.42
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Prednisolone, which is a potent, orally active corticosteroid and a glucocorticoid. It offers four times the anti-inflammatory effect of hydrocortisone with reduced salt and water retention, and is useful in ocular and anti-inflammatory research.

References : Prednisolone J. Am. Pharm. Assoc., 16(3), 143-146, 1976; Musson D. G. et al.: J. Chromatogr. 565(1-2), 89-102, 1991; Hahn B. H. et al.: Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 16(2), 163-170, 1973; Nowell P.C. Cancer Res., 21, 1518-21, 1961.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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