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Preladenant

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SI-7583

Preladenant, >98% (HPLC)

CAS No. : [377727-87-2]

Synonyms : SCH-420814

IUPAC Name : 2-(Furan-2-yl)-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine

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Chemical Properites
Mol. Formula :
C25H29N9O3
Mol. Weight :
503.57
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Preladenant binds the human A2A receptor with nanomolar affinity (Ki = 1.1 nM) and shows >1000‑fold selectivity over A1, A2B, and A3 receptors. Its potency and receptor specificity support its use in studies of A2A‑dependent physiological and pathological processes.

References : Hodgson R. A. et al.: Exp. Neurol., 225(2), 384-90, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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