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CAS No. : [2783961-86-2]
IUPAC Name : (S)-6-(4-(1-Phenylethoxy)phenyl)-4-(1,2,3,6-tetrahydropyridin-4-yl)-7H-pyrrolo[2,3-d]pyrimidine
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C25H24N4O | Mol. Weight : 396.49 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : PRMT5‑IN‑19 is a selective, orally active PRMT5 inhibitor (IC50 = 23.9 nM biochemical; 47 nM AlphaLISA) that blocks SAM‑pocket methyltransferase activity with strong selectivity over other PRMTs. It suppresses cancer cell proliferation by inducing apoptosis and serves as a useful tool compound for PRMT5‑related cancer research.
References : Rong D. et al.: J. Med. Chem., 65(11), 7854−7875, 2022.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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