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Isotopic Purity : 99 atom % D
Synonyms : Chloroguanide-d6; Chlorguanide-d6
IUPAC Name : N1-(4-Chlorophenyl)-N3-(propan-2-yl-d6)imidodicarbonimidic diamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C11H10D6ClN5 | Mol. Weight : 259.77 |
Appearance : White to Off-white solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Proguanil-d6 is a deuterium labelled version of Proguanil, which is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
References : Srivastava I. K. et al.: Antimicrob Agents Chemother., 43(6), 1334-9, 1999;Lochner M. et al.: J. Pharmacol Exp Ther., 351(3), 674-84, 2004; Stephen A. O. et al.: J. Toxicol Sci., 36(5), 587-99, 2011; Iguchi A. et al.: Vet. Parasitol., 197(3-4), 527-33, 2013.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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