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PRT-062607 hydrochloride

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SI-6318

PRT-062607 hydrochloride, >98% (HPLC)

CAS No. : [1370261-97-4]

Synonyms : P505-15 hydrochloride; PRT-2607 hydrochloride; BIIB-057 hydrochloride

IUPAC Name : 4-((3-(2H-1,2,3-Triazol-2-yl)phenyl)amino)-2-(((1R,2S)-2-aminocyclohexyl)amino)pyrimidine-5-carboxamide hydrochloride

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Chemical Properites
Mol. Formula :
C19H23N9O • HCl
Mol. Weight :
429.91
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PRT-062607 hydrochloride potently inhibits Syk at low‑nanomolar concentrations, blocking inflammatory responses and triggering apoptosis. It shows robust antitumor activity in xenograft models, making it a valuable tool for investigating Syk‑mediated immune regulation and cancer biology.

References : Spurgeon S. E. et al.: J. Pharmacol. Exp. Ther., 344(2):378-87, 2013; Coffey G. et al.: J. Pharmacol. Exp. Ther., 340(2), 350-9, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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