PRX-03140

SI-6737

PRX-03140, >98% (HPLC)

CAS No. : [869493-21-0]

Synonyms : VRX-03011 free base

IUPAC Name : 4-Hydroxy-7-isopropyl-6-oxo-N-(3-(piperidin-1-yl)propyl)-6,7-dihydrothieno[2,3-b]pyridine-5-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PRX‑03140 selectively activates 5‑HT₄ receptors (K_i= 110 nM in rat brain) and readily crosses the blood–brain barrier. By increasing cortical ACh and histamine release, it serves as a valuable tool for investigating cognitive dysfunction in Alzheimer’s disease models.

References : Johnson D. E. et al.: J. Pharmacol. Exp. Ther., 341(3), 681-91, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.