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PT-2385

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SI-8111

PT-2385, >98% (HPLC)

CAS No. : [1672665-49-4]

IUPAC Name : (S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C17H12F3NO4S
Mol. Weight :
383.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PT‑2385 selectively targets HIF‑2α with sub‑50 nM affinity, enabling precise modulation of HIF‑2α‑driven signaling pathways in cancer and hypoxia research.

References : Xie C. et al.: Nat. Med., 23(11), 1298-1308, 2017; Wallace E. M. et al.: Cancer Res., 76(18), 5491-500, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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