PTC-299

SI-7142

PTC-299, >98% (HPLC)

CAS No. : [1219951-09-3]

IUPAC Name : 4-Chlorophenyl (S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indole-2-carboxylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PTC299 inhibits VEGFA mRNA translation and potently targets DHODH, combining anti‑angiogenic and metabolic mechanisms. It shows good oral bioavailability and lacks off‑target kinase inhibition or myelosuppression, making it well suited for studies of hematologic cancers.

References : Cao L. et al.: Mol. Cancer Ther., 18(1), 3-16, 2019; Bender Ignacio R. A. et al.: J. Acquir. Immune Defic. Syndr., 72(1), 52-7, 2016; Packer R. J. et al.: J. Neurooncol., 121(1), 217-224, 2015; Zeng Z. et al.: Haematologica., 103(9), 1415-1417, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.