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PX-12

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SL-6150

PX-12, >98%

CAS No. : [141400-58-0]

MDL No. : MFCD18086851

Synonyms : IV-2

IUPAC Name : 2-[(1-Methylpropyl)dithio]-1H-imidazole; 2-(sec-Butyldisulfaneyl)-1H-imidazole

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10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C7H12N2S2
Mol. Weight :
188.31
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PX-12 is a potent thioredoxin-1 (Trx-1) inhibitor by irreversibly thioalkylation of Cys73 of Trx-1. Also, this is a COVID-19 related research chemical.

References : Welsh S. J. et al. Mol Cancer Ther., 2(3), 235-243, 2003; Kim Y. H. et al.: Cancer Chemother Pharmacol., 68(2), 405-413, 2011; You B. R. et al. Int. J. Oncol., 44(1), 301-308, 2014; Li G. Z. et al.: Am. J. Transl Res., 7(9), 1528-1540, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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