PX-20606

SI-6092

PX-20606, >98% (HPLC)

CAS No. : [2020096-17-5]

Synonyms : Px-102

IUPAC Name : 4-((1S,2S)-2-(2-Chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)cyclopropyl)benzoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PX‑20606 is a potent FXR agonist with low‑nanomolar activity (EC₅₀ ≈ 32–34 nM across FRET and M1H assays). It robustly activates farnesoid X receptor (FXR), supporting its use as a high‑quality tool compound for probing FXR‑regulated bile‑acid, metabolic, and hepatic pathways and as a promising lead for FXR‑targeted therapeutic development.

References : Romero F. A. et al.: J. Med. Chem., 63(10), 5031-5073, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.