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Pyrazole N-demethyl sildenafil

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SL-1549

Pyrazole N-demethyl sildenafil, >98%

CAS No. : [139755-95-6]

MDL No. : MFCD00908398

Synonyms : Desmethylsildenafil

IUPAC Name : 1-[[3-(4,7-Dihydroxy-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-piperazine

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Chemical Properites
Mol. Formula :
C21H28N6O4S
Mol. Weight :
460.55
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Pyrazole N-demethyl sildenafil is a novel an analog of Sildenafil, useful as cardiovascular agent.

References : Hucker H. et al.: Drug Metab. Disp., 1, 721,1973; Brogden R. et al.: Drugs, 16, 97,1978; Tulshian D. et al.: J. Med. Chem., 36, 1210,1993.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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