Pyrimethamine-d3

SI-5554

Pyrimethamine-d₃, >98% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1189936-99-9]

IUPAC Name : 5-(4-Chlorophenyl)-6-(ethyl-2,2,2-d₃)pyrimidine-2,4-diamine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Pyrimethamine-d₃ is a deuterium labelled version an analog of Pyrimethamine, which is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR).

References : Basco L. K. et al.: Am. J.Trop Med Hyg., 50(2), 193-9, 1994; Inceboz T. et al.: J. Drug Target., 21(2), 175-9, 2013; Wright P. D. et al.: Neurosci Lett., 482(3), 188-92, 2010; Martins-Duarte E. S. et al.: Exp Parasitol., 133(3), 294-9, 2013; Taylor W. R. et al.: Drug Saf., 27(1), 25-61, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.