QC-125

SI-7562

QC-125, >98% (HPLC)

IUPAC Name : (S)-6-(1-(1-Acetylazetidin-3-yl)-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-2-yl)-1-(3,4-difluorophenyl)piperidin-2-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : QC‑125 is a potent PROTAC degrader of p300/CBP, inducing efficient ubiquitination and proteasomal removal of these epigenetic coactivators. By degrading rather than inhibiting p300/CBP, QC‑125 provides strong suppression of p300/CBP‑dependent transcriptional programs, making it a valuable tool compound for probing epigenetic regulation and advancing next‑generation p300/CBP‑targeted therapeutics.

References : Chang Q. et al.: J. Med. Chem., 67(4), 2466-2486, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.