QC-182

SI-7557

QC-182, >98% (HPLC)

CAS No. : [3032646-96-8]

IUPAC Name : 5-(3-(4-(2-((S)-1-(3,4-Difluorophenyl)-6-oxopiperidin-2-yl)-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)azetidin-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : QC‑182 degrades p300/CBP with high potency, achieving a DC₅₀ of 93 nM in SK‑HEP‑1 cells. It suppresses proliferation of SK‑HEP‑1 and JHH7 HCC cell lines with sub‑micromolar IC₅₀ values, supporting its use in exploring epigenetic vulnerabilities and transcriptional dependencies in hepatocellular carcinoma.

References : Chang Q. et al.: J. Med. Chem., 67(4), 2466-2486, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.