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CAS No. : [950769-58-1]
Synonyms : AC-220; AC-708
IUPAC Name : 1-(5-(tert-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C29H32N6O4S | Mol. Weight : 560.67 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Quizartinib selectively targets FLT3 with high potency and also inhibits mutant PDGFRA and KIT isoforms, preventing receptor autophosphorylation. It effectively reduces proliferation and induces apoptosis in cancer cells, making it a valuable tool for investigating FLT3‑dependent oncogenic signaling.
References : Zarrinkar P. P. et al.: Blood, 114(14), 2984-2992, 2009; Puissant A. et al.: Cancer Cell., 25(2), 226-42, 2014; Sun X. et al.: Signal Transduct. Target Ther., 4, 64, 2019.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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