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Quizartinib

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SI-6936

Quizartinib, >98% (HPLC)

CAS No. : [950769-58-1]

Synonyms : AC-220; AC-708

IUPAC Name : 1-(5-(tert-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Chemical Properites
Mol. Formula :
C29H32N6O4S
Mol. Weight :
560.67
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Quizartinib selectively targets FLT3 with high potency and also inhibits mutant PDGFRA and KIT isoforms, preventing receptor autophosphorylation. It effectively reduces proliferation and induces apoptosis in cancer cells, making it a valuable tool for investigating FLT3‑dependent oncogenic signaling.

References : Zarrinkar P. P. et al.: Blood, 114(14), 2984-2992, 2009; Puissant A. et al.: Cancer Cell., 25(2), 226-42, 2014; Sun X. et al.: Signal Transduct. Target Ther., 4, 64, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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