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[(R)-2-(Phenylphosphonomethoxy)propyl]adenine-d5 (phenyl-d5)

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SL-1890

[(R)-2-(Phenylphosphonomethoxy)propyl]adenine-d5 (phenyl-d5), >98% (CP)

Isotopic Purity : 98 atom % D

CAS No. : [2131003-67-1]

Related CAS No. : [379270-35-6] of the unlabelled compound

Synonyms : [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester-d5

IUPAC Name : Phenyl-d5 hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

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Chemical Properites
Mol. Formula :
C15H13D5N5O4P
Mol. Weight :
368.34
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled analog of Tenofovir, an antiviral agent and intermediate of Tenofovir, which is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.

References : Murphy R. A. et al.: Int. J. Mol. Sci.18(3), 2017; Musumeci G. et al.: Sci. Rep. 7, 41018, 2017; Wahl A. et al.: Sci. Rep.7, 41098, 2017; Menne S. et al.: J. Antimicrob Agents Chemother., 49(7), 2720-2728, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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