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(R)-3-Ethynyl-3-hydroxy-1-methylpyrrolidin-2-one

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SI-1015

(R)-3-Ethynyl-3-hydroxy-1-methylpyrrolidin-2-one, >97%

CAS No. : [1451089-77-2]

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100MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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Chemical Properites
Mol. Formula :
C7H9NO2
Mol. Weight :
139.15
Appearance :
Light brown solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced heterocyclic intermediate in the preparation of NIK SMI1 related analogs, which is a potent, selective small molecule inhibitor of NF-κB.

References : Blaquiere N. et al.: J. Med. Chem., 61(15), 6801-6813, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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