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(R)-Crizotinib-d5 (piperidine-2,2,4,6,6-d5)

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SL-1360

(R)-Crizotinib-d5 (piperidine-2,2,4,6,6-d5), >98% (CP)

Isotopic Purity : 98 atom % D

CAS No. : [1395950-48-7]

Related CAS No. : [877399-52-5] of the unlabelled compound

Synonyms : PF 02341066-d5; PF 2341066-d5

IUPAC Name : 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl-d5)-1H-pyrazol-4-yl]-2-pyridinamine

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H17D5Cl2FN5O
Mol. Weight :
455.37
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Crizotinib, which is a potent inhibitor of c-Met and ALK. Crizotinib is an anti-cancer drug, used for the treatment of non-small cell lung carcinoma (NSCLC). It can be used as an analytical reference standard.

References : Tucker E. R. et al.: Mol. Oncol., 11(8), 996, 2017; Liu H. et al.: Cancer Discov., 8(3), 354, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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