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(R)-Diphenyl [[[1-[6-amino-9H-purin-9-yl]propan-2-yl]oxy]methyl]phosphonate

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SL-1891

(R)-Diphenyl [[[1-[6-amino-9H-purin-9-yl]propan-2-yl]oxy]methyl]phosphonate, >98%

CAS No. : [342631-41-8]

Synonyms : [(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid, diphenyl ester

IUPAC Name : Diphenyl (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

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Chemical Properites
Mol. Formula :
C21H22N5O4P
Mol. Weight :
439.40
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a reagent for the synthesis of amidate prodrugs of PMEA and PMPA. Also functions as a reagent in the preparation of Tenofovir alafenamide fumarate impurity.

References : Ballatore C. et al.: Bioorg. Med. Chem. Lett., 11, 1053,2001.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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