(R,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid

SI-1525

(R,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid, 97%

CAS No. : [1012341-48-8]

MDL No. : MFCD28386950

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	10.00		In Stock	Estimated to ship on 20 September 2026
5G	20.00		In Stock	Estimated to ship on 20 September 2026
25G	60.00		In Stock	Estimated to ship on 20 September 2026
100G	155.00		In Stock	Estimated to ship on 20 September 2026
500G	625.00		In Stock	Estimated to ship on 20 September 2026

Applications : This is an advanced key intermediate in the preparation of Sacubitril and related analogs, which is a first-in-class dual angiotensin receptor blocker −neprilysin inhibitor (ARNI) marketed for the treatment of chronic heart failure.

References : Flick C. A. et al.: J. Med. Chem., 60(15), 6480-6515, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.