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(R)-Leniolisib

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(R)-Leniolisib, >98%

CAS No. : [2987586-16-1]

IUPAC Name : (R)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one

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Chemical Properites
Mol. Formula :
C21H25F3N6O2
Mol. Weight :
450.47
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is enantiomer of Leniolisib, which is a potent and selective PI3Kδ inhibitor that shows promise for treating immunodeficiency disorders.

References : Singh K. et al.: Front Microbiol., 10, 1227, 2019; John O. L. et al.: Nature, 584(7822), 614-61, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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