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(R)-Letermovir

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(R)-Letermovir, >98%

CAS No. : [917389-37-8]

Synonyms : (R)-Letermovir impurity

IUPAC Name : (R)-2-(8-Fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetic acid

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Chemical Properites
Mol. Formula :
C29H28F4N4O4
Mol. Weight :
572.56
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is (R)-enatiomer of Letermovir, which is a novel anti-CMV compound, that targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. Additionally, it serves as a research chemical related to COVID-19.

References : Goldner T. et al.: J. Virol., 85(20), 10884-93, 2011; Lischka P. et al.: Antimicrob Agents Chemother., 54(3), 1290-7, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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