(R)-N-(3-(1-Hydroxy-2-((2-((3-methyl-1H-indazol-6-yl)oxy)ethyl)amino)ethyl)phenyl)methanesulfonamide dihydrochloride

SI-5039

(R)-N-(3-(1-Hydroxy-2-((2-((3-methyl-1H-indazol-6-yl)oxy)ethyl)amino)ethyl)phenyl)methanesulfonamide dihydrochloride, >98% (HPLC)

CAS No. : [1224854-08-3]

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
Note: SI-5039 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : This is a novel indazole derivative, and showed as human β3-adrenergic receptor (AR) agonistic activity (EC50 = 13 nM) and high selectivity (α1A/β3 = >769-fold). It was also inactive toward β1 and β2-ARs and showed dose dependent β3-AR mediated relaxation of marmoset urinary bladder smooth muscle, while it did not obviously affect heart rate or blood pressure (iv, 3 mg/kg) in anesthetized rats.

References : Wada Y. et al.: J. Med. Chem., 58(15), 6048-6057, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.