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(R)-N-Desacryloyl N-propionyl ibrutinib

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SL-3361

(R)-N-Desacryloyl N-propionyl ibrutinib, >98%

CAS No. : [1839099-22-7]

IUPAC Name : (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Chemical Properites
Mol. Formula :
C25H26N6O2
Mol. Weight :
442.51
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : (R)-N-Desacryloyl N-propionyl ibrutinib is an impurity of Ibrutinib, which is a selective, irreversible Bruton's tyrosine kinase (Btk) inhibitor, used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia.

References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107(29), 13075-13080, 2010; Herman S. E. et al.: Blood 117(23), 6287-6296, 2011; Chang B. Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7(1), 466, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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