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(R)-Netarsudil enantiomer hydrochloride

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(R)-Netarsudil enantiomer hydrochloride, >98%

Synonyms : Netarsudil impurity 6

IUPAC Name : (R)-4-(3-Amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate hydrochloride

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C28H27N3O3 • HCl
Mol. Weight :
490
Appearance :
Off-white solid (hygroscopic)
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an opposite enantiomer of Netarsudil, which is an inhibitor of ROCK. Netarsudil is currently in clinical trials for the treatment of glaucoma and ocular hypertension.

References : Sturdivant J. M. et al.: Bioorg Med Chem Lett., 26(10), 2475-80, 2016; Li G. et al.: Eur. J. Pharmacol., 787, 20-31, 2016; Ren R. et al.: Invest Ophthalmol Vis Sci., 57(14), 6197-6209, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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