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(R)-Nicardipine

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(R)-Nicardipine, >98%

CAS No. : [76093-35-1]

Synonyms : (R)-YC-93 free base

IUPAC Name : 3-(2-(Benzyl(methyl)amino)ethyl) 5-methyl (R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

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Chemical Properites
Mol. Formula :
C26H29N3O6
Mol. Weight :
479.53
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is the less active (R)-enantiomer of Nicardipine, which is a calcium channel blocker. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure.

References : Charnet P. et al.: Fundam Clin Pharmacol., 1(6), 413-31, 1987; Stamatiou R. et al.: Cardiovascular Research 114(1), S43, 2018; Sherrin H. B. New Drugs Annual., Cardiovascular Drugs, 3, 153-172, 1985.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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