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(R)-Pirtobrutinib

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SI-7565

(R)-Pirtobrutinib, >98% (HPLC)

CAS No. : [2101700-14-3]

Synonyms : (R)-LOXO-305

IUPAC Name : (R)-5-Amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4-carboxamide

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Chemical Properites
Mol. Formula :
C22H21F4N5O3
Mol. Weight :
479.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : (R)-Pirtobrutinib is the low‑activity enantiomer of Pirtobrutinib, a selective and reversible BTK inhibitor capable of inhibiting a broad spectrum of BTK C481 mutant variants. It is commonly used as an enantiomeric control in BTK‑signaling studies.

References : Gomez E. B. et al.: Blood, 134(1), 4644, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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