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CAS No. : [202271-90-7]
IUPAC Name : (R)-4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C13H11N3O4 | Mol. Weight : 273.25 |
Appearance : Solid | Melting Point : Not available |
Solubility : DMSO | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : This is an (R)-enantiomer of Pomalidomide, which is a third-generation immunomodulatory agent that acts as molecular glue by binding to E3 ligase cereblon and promoting degradation of Ikaros transcription factors.
References : Zhu Y. X. et al.: Leuk Lymphoma, 54(4), 683-7, 2013; Hernandez-Ilizaliturri F. et al.: Clin Cancer Res., 11(16), 5984-92., 2005; Schafer P. H. et al.: J. Pharmacol Exp Ther. 305(3), 1222-32, 2003; Li Z. et al.: PLoS One, 8(8), e71754, 2013; Lu J. et al.: Chem Biol., 22(6), 755-63, 2015; Liu D. et al.: Gen Comp Endocrinol., 228, 1-8, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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