(R,R)-VVD-118313

SI-8133

(R,R)-VVD-118313, >98% (HPLC)

CAS No. : [2875046-31-2]

IUPAC Name : 1-((R)-3-(3,4-Dichlorophenyl)piperidin-1-yl)-3-((R)-1-(methylsulfonyl)pyrrolidin-3-yl)prop-2-yn-1-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : (R,R)-VVD‑118313 represents the isomer of VVD‑118313, a selective JAK1 inhibitor that disrupts JAK1‑dependent trans‑phosphorylation and cytokine signaling pathways relevant to cancer biology. Its alkyne functionality enables CuAAC click chemistry with azide‑bearing partners, supporting chemical biology and probe‑development applications.

References : Kavanagh E. M. et al.: Nat. Chem. Biol., 18(12), 1388-1398, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.