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(R)-Repaglinide

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SL-6783

(R)-Repaglinide, >98%

CAS No. : [147852-26-4]

Synonyms : Repaglinide EP impurity E

IUPAC Name : (R)-2-Ethoxy-4-(2-((3-methyl-1-(2-(piperidin-1-yl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid

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Chemical Properites
Mol. Formula :
C27H36N2O4
Mol. Weight :
452.60
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : (R)-Repaglinide is an opposite enantiomer of (S)-Repaglinide. A potassium channel blocker, which lowers blood glucose by stimulating the release of insulin from the pancreas, used to treat for the type II diabetes.

References : Hansen A. M. et al.: Br. J. Pharmacol., 144(4), 551-557, 2005; Okada M. et al.: Biochem J. 375(Pt 1), 87-97, 2003; Laghmich A. et al.: Eur. J. Pharmacol., 348(2-3), 265-270,1998; Ladriere L. et al. Eur J Pharmacol., 335(2-3), 227-234,1997.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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