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(R,S)-Palonosetron hydrochloride

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SL-11204

(R,S)-Palonosetron hydrochloride, >98%

IUPAC Name : (S)-2-((R)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline hydrochloride

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C19H26N2 • HCl
Mol. Weight :
318.89
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a diastereomer of Palonosetron, which is a 5-HT3 receptor antagonist primarily indicated for the prevention of acute, delayed, and overall chemotherapy-induced nausea and vomiting. Palonosetron demonstrates moderate anti-flavivirus activity and exhibits strong anti-Zika virus effects in mammalian cell models. Additionally, Palonosetron has been found to possess antidepressant properties.

References : Barrows J. N. et al.: Cell host & microbe 20(2), 259-270, 2016; Rojas C. et al.: Anesthesia & Analgesia 107(2), 469-478, 2008; Wallenborn J. et al. Therapeutics 2 CMT-S4016, 2010; Sepúlveda-Vildósola et al.: Archives of medical research 39(6), 601-606, 2008; Sharma J. et al.: National Journal of Pharmacology and Therapeutics, 2023, 1(2), 98-100, 2023; Rojas C. et al.: J. Pharmacol Exp Ther., 335(2), 362-8, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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