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(R)-SCH-546738

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SI-7157

(R)-SCH-546738, >98% (HPLC)

CAS No. : [2181148-54-7]

IUPAC Name : (R)-3-Amino-6-chloro-5-(4-(1-(4-chlorobenzyl)piperidin-4-yl)-3-ethylpiperazin-1-yl)pyrazine-2-carboxamide

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Chemical Properites
Mol. Formula :
C23H31Cl2N7O
Mol. Weight :
492.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : (R)-SCH-546738 is the (R)‑isomer of SCH-546738, an orally active, non‑competitive CXCR3 antagonist with a Ki of 0.4 nM for the human CXCR3 receptor.

References : Jenh C. H. et al.: B.M.C. Immunol., 13, 2 , 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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