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(R)-Siremadlin enantiomer

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SI-6499

(R)-Siremadlin enantiomer, >98% (HPLC)

CAS No. : [1448867-42-2]

Synonyms : (R)-NVP-HDM-201 enantiomer; (R)-HDM-201 enantiomer

IUPAC Name : (R)-5-(5-Chloro-1-methyl-2-oxo-1,2-dihydropyridin-3-yl)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-1-isopropyl-5,6-dihydropyrrolo[3,4-d]imidazol-4(1H)-one

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Chemical Properites
Mol. Formula :
C26H24Cl2N6O4
Mol. Weight :
555.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : The Siremadlin (R)-enantiomer is the stereochemical counterpart of Siremadlin, a highly specific MDM2 antagonist that blocks the MDM2–p53 interface. The R form is useful as a reference or control compound in studies probing MDM2‑regulated p53 activation.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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