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CAS No. : [942195-56-4]
IUPAC Name : (R)-4-((5,7-Difluorochroman-4-yl)oxy)-N,N,2-trimethyl-1H-benzo[d]imidazole-6-carboxamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 10MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 25MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 50MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 100MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C20H19F2N3O3 | Mol. Weight : 387.39 |
Appearance : Off-white solid | Melting Point : Not available |
Solubility : MeOH | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : This is an opposite enantiomer of Tegoprazan, which is a potassium-competitive acid blocker that acts as a reversible, orally active, and selective inhibitor of gastric H+/K+-ATPase. It reduces gastric acid secretion and motility in porcine, canine, and human H+/K+-ATPase in vitro, with IC50 values between 0.29-0.52 μM. Studies indicate that Tegoprazan improves colitis and enhances intestinal epithelial barrier function in mice. Tegoprazan is used in research related to inflammatory bowel disease, gastric acid-related conditions, and motility impairments.
References : Son M. et al.: Front Immunol.,13, 870817, 2022; Kim D. K, et al.: J. Pharmacol Exp Ther., 369(3), 318-327, 2019; Takahashi N. et al.: J. Pharmacol Exp Ther., 364(2), 275-286, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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