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(R)-tert-Butyl 3-(4-cyano-3-fluorophenoxy)-4-methylenepyrrolidine-1-carboxylate

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SI-1246

(R)-tert-Butyl 3-(4-cyano-3-fluorophenoxy)-4-methylenepyrrolidine-1-carboxylate, 97%

CAS No. : [2215855-68-6]

Price And Availability
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100MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
500MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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Chemical Properites
Mol. Formula :
C17H19FN2O3
Mol. Weight :
318.34
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key chiral intermediate in the preparation of GSK-3395879 and related analogs, which is a novel potent, selective, orally bioavailable antagonist of TRPV4.

References : Brnardic J. E. et al.: J. Med. Chem., 61(21), 9738-9755, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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