(R)-Vorbipiprant

SI-7082

(R)-Vorbipiprant, >98% (HPLC)

CAS No. : [2502965-92-4]

Synonyms : (R)-CR-6086

IUPAC Name : (R)-4-(1-(6-(4-(Trifluoromethyl)benzyl)-6-azaspiro[2.5]octane-5-carboxamido)cyclopropyl)benzoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : (R)-Vorbipiprant selectively targets the EP4 receptor with nanomolar affinity (Ki = 16.6 nM) and blocks PGE₂‑dependent cAMP production (IC₅₀= 22 nM). It shows pronounced immunomodulatory and anti‑angiogenic effects and improves outcomes in murine collagen‑induced arthritis.

References : Caselli G. et al.: Arthritis Res. Ther., 20(1), 39, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.