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rac-Atuveciclib

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SI-6836

rac-Atuveciclib, >98% (HPLC)

CAS No. : [1414943-88-6]

Synonyms : rac-BAY-1143572

IUPAC Name : (3-((4-(4-Fluoro-2-methoxyphenyl)-1,3,5-triazin-2-yl)amino)benzyl)(imino)(methyl)-l6-sulfanone

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Chemical Properites
Mol. Formula :
C18H18FN5O2S
Mol. Weight :
387.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : rac-Atuveciclib is the racemic mixture of Atuveciclib, a selective oral P‑TEFb/CDK9 inhibitor with nanomolar potency (IC50 = 13 nM against CDK9/CycT1). It is useful for research on CDK9‑dependent transcriptional control and oncogenic signaling.

References : Scholz A. et al.: AACR; Cancer Res., 76(14), 3022, 2016; Scholz A. et al.: AACR; Cancer Res., 75(15), DDT02-02, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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